Primary sequences of proteinlike copolymers: Levy-flight-type long-range correlations.

نویسندگان

  • E N Govorun
  • V A Ivanov
  • A R Khokhlov
  • P G Khalatur
  • A L Borovinsky
  • A Y Grosberg
چکیده

We consider the statistical properties of primary sequences of two-letter HP copolymers (H for hydrophobic and P for polar) designed to have water soluble globular conformations with H monomers shielded from water inside the shell of P monomers. We show, both by computer simulations and by exact analytical calculation, that for large globules and flexible polymers such sequences exhibit long-range correlations which can be described by Levy-flight statistics.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Coil-globule transition for regular, random, and specially designed copolymers: Monte Carlo simulation and self-consistent field theory.

The coil-globule transition has been studied for A-B copolymer chains both by means of lattice Monte Carlo (MC) simulations using bond fluctuation algorithm and by a numerical self-consistent-field (SCF) method. Copolymer chains of fixed length with A and B monomeric units with regular, random, and specially designed (proteinlike) primary sequences have been investigated. The dependence of the ...

متن کامل

Random sequences with power-law correlations exhibit proteinlike behavior.

We use a replica approach to investigate the thermodynamic properties of the random heteropolymers with persistent power-law correlations in monomer sequence. We show that this type of sequences possess proteinlike properties. In particular, we show that they can fold into stable unique three-dimensional structure (the "native" structure, in protein terminology) through two different types of p...

متن کامل

“Sequence space soup” of proteins and copolymers

To study the protein folding problem, we use exhaustive computer enumeration to explore “sequence space soup,” an imaginary solution containing the “native” conformations (i.e., of lowest free energy) under folding conditions, of every possible copolymer sequence. The model is of short self-avoiding chains of hydrophobic (H) and polar (P) monomers configured on the two-dimensional square lattic...

متن کامل

Species Diversity in Rock-Paper-Scissors Game Coupling with Levy Flight

Rock–paper–scissors (RPS) game is a nice model to study the biodiversity in ecosystem. However, the previous studies only consider the nearestneighborinteraction among the species. In this paper, taking the long range migration into account, the effects of the interplay between nearest-neighbor-interaction and long-range-interaction of Levy flight with distance distribution h l (-0.3<h<-0.1) in...

متن کامل

A Hybrid Data Clustering Algorithm Using Modified Krill Herd Algorithm and K-MEANS

Data clustering is the process of partitioning a set of data objects into meaning clusters or groups. Due to the vast usage of clustering algorithms in many fields, a lot of research is still going on to find the best and efficient clustering algorithm. K-means is simple and easy to implement, but it suffers from initialization of cluster center and hence trapped in local optimum. In this paper...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Physical review. E, Statistical, nonlinear, and soft matter physics

دوره 64 4 Pt 1  شماره 

صفحات  -

تاریخ انتشار 2001